Publications

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1993
Dunbar DR, Moonie PA, Swingler RJ, Davidson D, Roberts R, Holt IJ. Maternally transmitted partial direct tandem duplication of mitochondrial DNA associated with diabetes mellitus. Hum Mol Genet. 1993;2(10):1619-24. Abstract
1995
Dunbar DR, Moonie PA, Jacobs HT, Holt IJ. Different cellular backgrounds confer a marked advantage to either mutant or wild-type mitochondrial genomes. Proc Natl Acad Sci USA. 1995;92(14):6562-6. Abstract
1996
Dunbar DR, Moonie PA, Zeviani M, Holt IJ. Complex I deficiency is associated with 3243G:C mitochondrial DNA in osteosarcoma cell cybrids. Hum Mol Genet. 1996;5(1):123-29. Abstract
1997
Dunbar DR, Shibasaki Y, Dobbie L, Andersson B, Brookes AJ. In situ hybridisation mapping of genomic clones for five human respiratory chain complex I genes. Cytogenet Cell Genet. 1997;78(1):21-4. Abstract
Holt IJ, Dunbar DR, Jacobs HT. Behaviour of a population of partially duplicated mitochondrial DNA molecules in cell culture: segregation, maintenance and recombination dependent upon nuclear background. Hum Mol Genet. 1997;6(8):1251-60. Abstract
1998
El Meziane A, Lehtinen SK, Hance N, Nijtmans LG, Dunbar D, Holt IJ, et al. A tRNA suppressor mutation in human mitochondria. Nat Genet. 1998;18(4):350-3. Abstract
Morrow JA, Collie IT, Dunbar DR, Walker GB, Shahid M, Hill DR. Molecular cloning and functional expression of the human glycine transporter GlyT2 and chromosomal localisation of the gene in the human genome. FEBS Lett. 1998;439(3):334-40. Abstract
2005
Thomson PA, Wray NR, Thomson AM, Dunbar DR, Grassie MA, Condie A, et al. Sex-specific association between bipolar affective disorder in women and GPR50, an X-linked orphan G protein-coupled receptor. Mol Psychiatry. 2005;10(5):470-8. Abstract
2006
Mullins JJ, Mullins LJ, Dunbar DR, Brammar WJ, Gross KW, Morley SD. Identification of a human ortholog of the mouse Dcpp gene locus, encoding a novel member of the CSP-1/Dcpp salivary protein family. Physiological genomics. 2006;28:129-40. Abstract
2007
Semprini S, Troup TJ, Kotelevtseva N, King K, Davis JR, Mullins LJ, et al. Cryptic loxP sites in mammalian genomes: genome-wide distribution and relevance for the efficiency of BAC/PAC recombineering techniques. Nucleic acids research. 2007;35:1402-10. Abstract
Sheahan S, Bellamy CO, Dunbar DR, Harrison DJ, Prost S. Deficiency of G1 regulators P53, P21Cip1 and/or pRb decreases hepatocyte sensitivity to TGFbeta cell cycle arrest. BMC cancer. 2007;7:215. Abstract
Brown SB, Tucker CS, Ford C, Lee Y, Dunbar DR, Mullins JJ. Class III antiarrhythmic methanesulfonanilides inhibit leukocyte recruitment in zebrafish. Journal of leukocyte biology. 2007;82:79-84. Abstract
2009
Manning JR, Hedley A, Mullins JJ, Dunbar DR. Automated seeding of specialised wiki knowledgebases with BioKb. BMC bioinformatics. 2009;10:291. Abstract
Harmar AJ, Hills RA, Rosser EM, Jones M, Buneman PO, Dunbar DR, et al. IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels. Nucleic acids research. 2009;37:D680-5. Abstract
Liu X, Bellamy CO, Bailey MA, Mullins LJ, Dunbar DR, Kenyon CJ, et al. Angiotensin-converting enzyme is a modifier of hypertensive end organ damage. The Journal of biological chemistry. 2009;284:15564-72. Abstract
Dumitriu IE, Dunbar DR, Howie SE, Sethi T, Gregory CD. Human dendritic cells produce TGF-beta 1 under the influence of lung carcinoma cells and prime the differentiation of CD4+CD25+Foxp3+ regulatory T cells. Journal of immunology (Baltimore, Md. : 1950). 2009;182:2795-807. Abstract
2010
Manning JR, Bailey MA, Soares DC, Dunbar DR, Mullins JJ. In silico structure-function analysis of pathological variation in the HSD11B2 gene sequence. Physiological genomics. 2010;42:319-30. Abstract
Fox KA, Carruthers KF, Dunbar DR, Graham C, Manning JR, De Raedt H, et al. Underestimated and under-recognized: the late consequences of acute coronary syndrome (GRACE UK-Belgian Study). European heart journal. 2010. Abstract
Dunbar DR, Khaled H, Evans LC, Al-Dujaili EA, Mullins LJ, Mullins JJ, et al. Transcriptional and physiological responses to chronic ACTH treatment by the mouse kidney. Physiological genomics. 2010;40:158-66. Abstract
Buysschaert I, Carruthers KF, Dunbar DR, Peuteman G, Rietzschel E, Belmans A, et al. A variant at chromosome 9p21 is associated with recurrent myocardial infarction and cardiac death after acute coronary syndrome: the GRACE Genetics Study. European heart journal. 2010;31:1132-41. Abstract
2011
Morton NM, Nelson YB, Michailidou Z, Di Rollo EM, Ramage L, Hadoke PW, et al. A stratified transcriptomics analysis of polygenic fat and lean mouse adipose tissues identifies novel candidate obesity genes. PLoS ONE. 2011;6(9):e23944. Abstract
Conway BR, Rennie J, Bailey MA, Dunbar DR, Manning JR, Bellamy CO, et al. Hyperglycemia and Renin-Dependent Hypertension Synergize to Model Diabetic Nephropathy. Journal of the American Society of Nephrology : JASN. 2011. Abstract
Wamil M, Battle JH, Turban S, Kipari T, Seguret D, de Peixoto RS, et al. Novel Fat Depot-Specific Mechanisms Underlie Resistance to Visceral Obesity and Inflammation in 11{beta}-Hydroxysteroid Dehydrogenase Type 1-Deficient Mice. Diabetes. 2011. Abstract
2012
Bolukbasi E, Vass S, Cobbe N, Nelson B, Simossis V, Dunbar DR, et al. Drosophila poly suggests a novel role for the Elongator complex in insulin receptor–target of rapamycin signalling. Open Biology. 2012;2. Abstract
Turban S, Liu X, Ramage L, Webster SP, Walker BR, Dunbar DR, et al. Optimal Elevation of β-Cell 11β-Hydroxysteroid Dehydrogenase Type 1 Is a Compensatory Mechanism that Prevents High Fat Diet-Induced β-Cell Failure. Diabetes. 2012. Abstract