Publications

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1990
Dalziel HH, Gray GA, Drummond RM, Furman BL, Sneddon P. Investigation of the selectivity of alpha, beta-methylene ATP in inhibiting vascular responses of the rat in vivo and in vitro. Br J Pharmacol. 1990;99(4):820-4. Abstract
Gray GA, Furman BL, Parratt JR. Endotoxin-induced impairment of vascular reactivity in the pithed rat: role of arachidonic acid metabolites. Circ Shock. 1990;31(4):395-406. Abstract
Gray GA, Julou-Schaeffer G, Oury K, Fleming I, Parratt JR, Stoclet JC. An L-arginine-derived factor mediates endotoxin-induced vascular hyposensitivity to calcium. Eur J Pharmacol. 1990;191(1):89-92. Abstract
Julou-Schaeffer G, Gray GA, Fleming I, Schott C, Parratt JR, Stoclet JC. Loss of vascular responsiveness induced by endotoxin involves L-arginine pathway. Am J Physiol. 1990;259(4 Pt 2):H1038-43. Abstract
Fleming I, Gray GA, Julou-Schaeffer G, Parratt JR, Stoclet JC. Incubation with endotoxin activates the L-arginine pathway in vascular tissue. Biochem Biophys Res Commun. 1990;171(2):562-8. Abstract
1991
Fleming I, Gray GA, Schott C, Stoclet JC. Inducible but not constitutive production of nitric oxide by vascular smooth muscle cells. Eur J Pharmacol. 1991;200(2-3):375-6.
Gray GA, Schott C, Julou-Schaeffer G, Fleming I, Parratt JR, Stoclet JC. The effect of inhibitors of the L-arginine/nitric oxide pathway on endotoxin-induced loss of vascular responsiveness in anaesthetized rats. Br J Pharmacol. 1991;103(1):1218-24. Abstract
Fleming I, Julou-Schaeffer G, Gray GA, Parratt JR, Stoclet JC. Evidence that an L-arginine/nitric oxide dependent elevation of tissue cyclic GMP content is involved in depression of vascular reactivity by endotoxin. Br J Pharmacol. 1991;103(1):1047-52. Abstract
1992
Schuller F, Fleming I, Stoclet JC, Gray GA. Effect of endotoxin on circulating cyclic GMP in the rat. Eur J Pharmacol. 1992;212(1):93-6. Abstract
Schuller F, Fleming I, Stoclet JC, Gray GA. Effect of endotoxin on circulating cyclic GMP in the rat. Eur J Pharmacol. 1992;212(1):93-6. Abstract
Clozel M, Gray GA, Breu V, Löffler BM, Osterwalder R. The endothelin ETB receptor mediates both vasodilation and vasoconstriction in vivo. Biochem Biophys Res Commun. 1992;186(2):867-73. Abstract
1993
Clozel M, Breu V, Gray GA, Löffler BM. In vivo pharmacology of Ro 46-2005, the first synthetic nonpeptide endothelin receptor antagonist: implications for endothelin physiology. J Cardiovasc Pharmacol. 1993;22 Suppl 8:S377-9. Abstract
Fleming I, Gray GA, Stoclet JC. Influence of endothelium on induction of the L-arginine-nitric oxide pathway in rat aortas. Am J Physiol. 1993;264(4 Pt 2):H1200-7. Abstract
Schott CA, Gray GA, Stoclet JC. Dependence of endotoxin-induced vascular hyporeactivity on extracellular L-arginine. Br J Pharmacol. 1993;108(1):38-43. Abstract
Paya D, Gray GA, Stoclet JC. Effects of methylene blue on blood pressure and reactivity to norepinephrine in endotoxemic rats. J Cardiovasc Pharmacol. 1993;21(6):926-30. Abstract
Paya D, Gray GA, Fleming I, Stoclet JC. Effect of dexamethasone on the onset and persistence of vascular hyporeactivity induced by E. coli lipopolysaccharide in rats. Circ Shock. 1993;41(2):103-12. Abstract
Gray GA, Clozel M, Clozel JP, Baumgartner HR. Effects of calcium channel blockade on the aortic intima in spontaneously hypertensive rats. Hypertension. 1993;22(4):569-76. Abstract
Clozel M, Breu V, Burri K, Cassal JM, Fischli W, Gray GA, et al. Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist. Nature. 1993;365(6448):759-61. Abstract
1994
Teerlink JR, Gray GA, Clozel M, Clozel JP. Increased vascular responsiveness to norepinephrine in rats with heart failure is endothelium dependent. Dissociation of basal and stimulated nitric oxide release. Circulation. 1994;89(1):393-401. Abstract
Clozel M, Breu V, Gray GA, Kalina B, Löffler BM, Burri K, et al. Pharmacological characterization of bosentan, a new potent orally active nonpeptide endothelin receptor antagonist. J Pharmacol Exp Ther. 1994;270(1):228-35. Abstract
Gray GA, Löffler BM, Clozel M. Characterization of endothelin receptors mediating contraction of rabbit saphenous vein. Am J Physiol. 1994;266(3 Pt 2):H959-66. Abstract
1995
Clozel M, Gray GA. Are there different ETB receptors mediating constriction and relaxation? J Cardiovasc Pharmacol. 1995;26 Suppl 3:S262-4. Abstract
Gray GA, Breu V, Clozel M. Endothelin receptors that modulate contraction of the rat fundus. J Cardiovasc Pharmacol. 1995;26 Suppl 3:S126-9. Abstract
Roux S, Löffler BM, Gray GA, Sprecher U, Clozel M, Clozel JP. The role of endothelin in experimental cerebral vasospasm. Neurosurgery. 1995;37(1):78-85; discussion 85-6. Abstract
Véniant M, Gray GA, Heudes D, Ménard J, Clozel JP. Structural changes and cyclic GMP content of the aorta after calcium antagonism or angiotensin converting enzyme inhibition in renovascular hypertensive rats. J Hypertens. 1995;13(7):731-7. Abstract