Publications

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2006
Hodkinson PS, Elliott T, Wong WS, Rintoul RC, Mackinnon AC, Haslett C, et al. ECM overrides DNA damage-induced cell cycle arrest and apoptosis in small-cell lung cancer cells through beta1 integrin-dependent activation of PI3-kinase. Cell Death Differ. 2006;13(10):1776-88. Abstract
2003
Waters CM, Mackinnon AC, Cummings J, Tufail-Hanif U, Jodrell D, Haslett C, et al. Increased gastrin-releasing peptide (GRP) receptor expression in tumour cells confers sensitivity to [Arg6,D-Trp7,9,NmePhe8]-substance P (6-11)-induced growth inhibition. Br J Cancer. 2003;88(11):1808-16. Abstract
2001
Hirani N, Antonicelli F, Strieter RM, Wiesener MS, Ratcliffe PJ, Haslett C, et al. The regulation of interleukin-8 by hypoxia in human macrophages–a potential role in the pathogenesis of the acute respiratory distress syndrome (ARDS). Molecular medicine (Cambridge, Mass.). 2001;7:685-97. Abstract
Taylor EL, Megson IL, Haslett C, Rossi AG. Dissociation of DNA fragmentation from other hallmarks of apoptosis in nitric oxide-treated neutrophils: differences between individual nitric oxide donor drugs. Biochemical and biophysical research communications. 2001;289:1229-36. Abstract
Whittle AT, Davis M, Shovlin CL, Ganly PS, Haslett C, Greening AP. Alveolar macrophage activity and the pulmonary complications of haematopoietic stem cell transplantation. Thorax. 2001;56:941-6. Abstract
2000
Mackinnon AC, Waters C, Rahman I, Harani N, Rintoul R, Haslett C, et al. [Arg(6), D-Trp(7,9), N(me)Phe(8)]-substance P (6-11) (antagonist G) induces AP-1 transcription and sensitizes cells to chemotherapy. Br J Cancer. 2000;83(7):941-8. Abstract
1999
Liu Y, Cousin JM, Hughes J, Van Damme J, Seckl JR, Haslett C, et al. Glucocorticoids promote nonphlogistic phagocytosis of apoptotic leukocytes. Journal of immunology (Baltimore, Md. : 1950). 1999;162:3639-46. Abstract
Sethi T, Rintoul RC, Moore SM, Mackinnon AC, Salter D, Choo C, et al. Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo. Nat Med. 1999;5(6):662-8. Abstract
Mackinnon AC, Armstrong RA, Waters CM, Cummings J, Smyth JF, Haslett C, et al. [Arg6,D-Trp7,9,NmePhe8]-substance P (6-11) activates JNK and induces apoptosis in small cell lung cancer cells via an oxidant-dependent mechanism. Br J Cancer. 1999;80(7):1026-34. Abstract
1996
Tallett A, Chilvers ER, Mackinnon AC, Haslett C, Sethi T. Neuropeptides stimulate tyrosine phosphorylation and tyrosine kinase activity in small cell lung cancer cell lines. Peptides. 1996;17(4):665-73. Abstract