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McCormick JA, Lyons V, Noble J, Ester W, Meaney MJ, Seckl JR, et al. Tissue-specific differences in rat glucocorticoid receptor gene transcriptional regulation. Biochem Soc Trans. 1998;26(3):S207.
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Yau JL, Noble J, Hibberd C, Seckl JR. Short-term administration of fluoxetine and venlafaxine decreases corticosteroid receptor mRNA expression in the rat hippocampus. Neuroscience letters. 2001;306:161-4. Abstract
Yau JL, Olsson T, Noble J, Seckl JR. Serotonin receptor subtype gene expression in the hippocampus of aged rats following chronic amitriptyline treatment. Brain research. Molecular brain research. 1999;70:282-7. Abstract
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Sooy K, Webster SP, Noble J, Binnie M, Walker BR, Seckl JR, et al. Partial deficiency or short-term inhibition of 11beta-hydroxysteroid dehydrogenase type 1 improves cognitive function in aging mice. J Neurosci. 2010;30(41):13867-72. Abstract
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Mattsson C, Lai M, Noble J, McKinney E, Yau JL, Seckl JR, et al. Obese Zucker rats have reduced mineralocorticoid receptor and 11beta-hydroxysteroid dehydrogenase type 1 expression in hippocampus-implications for dysregulation of the hypothalamic-pituitary-adrenal axis in obesity. Endocrinology. 2003;144:2997-3003. Abstract
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Yau JL, Noble J, Kenyon CJ, Hibberd C, Kotelevtsev Y, Mullins JJ, et al. Lack of tissue glucocorticoid reactivation in 11beta -hydroxysteroid dehydrogenase type 1 knockout mice ameliorates age-related learning impairments. Proceedings of the National Academy of Sciences of the United States of America. 2001;98:4716-21. Abstract
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Benediktsson R, Lindsay RS, Noble J, Seckl JR, Edwards CR. Glucocorticoid exposure in utero: new model for adult hypertension. Lancet. 1993;341:339-41. Abstract
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Yau JL, McNair KM, Noble J, Brownstein D, Hibberd C, Morton N, et al. Enhanced hippocampal long-term potentiation and spatial learning in aged 11beta-hydroxysteroid dehydrogenase type 1 knock-out mice. J Neurosci. 2007;27(39):10487-96. Abstract
Yau JL, Hibberd C, Noble J, Seckl JR. The effect of chronic fluoxetine treatment on brain corticosteroid receptor mRNA expression and spatial memory in young and aged rats. Brain research. Molecular brain research. 2002;106:117-23. Abstract
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Yau JL, Noble J, Chapman KE, Seckl JR. Differential regulation of variant glucocorticoid receptor mRNAs in the rat hippocampus by the antidepressant fluoxetine. Brain research. Molecular brain research. 2004;129:189-92. Abstract
Yau JL, Rasmuson S, Andrew R, Graham M, Noble J, Olsson T, et al. Dehydroepiandrosterone 7-hydroxylase CYP7B: predominant expression in primate hippocampus and reduced expression in Alzheimer’s disease. Neuroscience. 2003;121:307-14. Abstract
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Yau JL, Noble J, Seckl JR. Continuous blockade of brain mineralocorticoid receptors impairs spatial learning in rats. Neuroscience letters. 1999;277:45-8. Abstract
Yau JL, Noble J, Hibberd C, Rowe WB, Meaney MJ, Morris RG, et al. Chronic treatment with the antidepressant amitriptyline prevents impairments in water maze learning in aging rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2002;22:1436-42. Abstract
Yau JL, Kelly PA, Olsson T, Noble J, Seckl JR. Chronic amitriptyline administration increases serotonin transporter binding sites in the hippocampus of aged rats. Neuroscience letters. 1999;261:183-5. Abstract
Yau JL, Noble J, Graham M, Seckl JR. Central administration of a cytochrome P450-7B product 7 alpha-hydroxypregnenolone improves spatial memory retention in cognitively impaired aged rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2006;26:11034-40. Abstract
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Yau JL, Noble J, Seckl JR. Acute restraint stress increases 5-HT7 receptor mRNA expression in the rat hippocampus. Neuroscience letters. 2001;309:141-4. Abstract
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McCormick JA, Lyons V, Jacobson MD, Noble J, Diorio J, Nyirenda M, et al. 5’-heterogeneity of glucocorticoid receptor messenger RNA is tissue specific: differential regulation of variant transcripts by early-life events. Molecular endocrinology (Baltimore, Md.). 2000;14:506-17. Abstract
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Holmes MC, Carter RN, Noble J, Chitnis S, Dutia A, Paterson JM, et al. 11beta-hydroxysteroid dehydrogenase type 1 expression is increased in the aged mouse hippocampus and parietal cortex and causes memory impairments. J Neurosci. 2010;30(20):6916-20. Abstract
Yau JL, Noble J, Seckl JR. 11beta-hydroxysteroid dehydrogenase type 1 deficiency prevents memory deficits with aging by switching from glucocorticoid receptor to mineralocorticoid receptor-mediated cognitive control. J Neurosci. 2011;31(11):4188-93. Abstract
Sandeep TC, Yau JL, MacLullich AM, Noble J, Deary IJ, Walker BR, et al. 11Beta-hydroxysteroid dehydrogenase inhibition improves cognitive function in healthy elderly men and type 2 diabetics. Proceedings of the National Academy of Sciences of the United States of America. 2004;101:6734-9. Abstract