Publications

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A
Adamson KA, Pearce SH, Lamb JR, Seckl JR, Howie SE. A comparative study of mRNA and protein expression of the autoimmune regulator gene (Aire) in embryonic and adult murine tissues. The Journal of pathology. 2004;202:180-7. Abstract
Andrew R, Gale CR, Walker BR, Seckl JR, Martyn CN. Glucocorticoid metabolism and the Metabolic Syndrome: associations in an elderly cohort. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. 2002;110:284-90. Abstract
B
Bailey MA, Paterson JM, Hadoke PW, Wrobel N, Bellamy CO, Brownstein DG, et al. A switch in the mechanism of hypertension in the syndrome of apparent mineralocorticoid excess. Journal of the American Society of Nephrology : JASN. 2008;19:47-58. Abstract
Bean R, Seckl JR, Lathe R, Martin C. Ontogeny of the neurosteroid enzyme Cyp7b in the mouse. Molecular and cellular endocrinology. 2001;174:137-44. Abstract
Benediktsson R, Lindsay RS, Noble J, Seckl JR, Edwards CR. Glucocorticoid exposure in utero: new model for adult hypertension. Lancet. 1993;341:339-41. Abstract
Birzniece V, Johansson IM, Wang MD, Seckl JR, Bäckström T, Olsson T. Serotonin 5-HT(1A) receptor mRNA expression in dorsal hippocampus and raphe nuclei after gonadal hormone manipulation in female rats. Neuroendocrinology. 2001;74:135-42. Abstract
Blackhurst G, Strachan MW, Collie D, Gregor A, Statham PF, Seckl JE. The treatment of a thyrotropin-secreting pituitary macroadenoma with octreotide in twin pregnancy. Clinical endocrinology. 2002;57:401-4. Abstract
Brown RW, Chapman KE, Edwards CR, Seckl JR. Human placental 11 beta-hydroxysteroid dehydrogenase: evidence for and partial purification of a distinct NAD-dependent isoform. Endocrinology. 1993;132(6):2614-21. Abstract
Brown RW, Chapman KE, Kotelevtsev Y, Yau JL, Lindsay RS, Brett L, et al. Cloning and production of antisera to human placental 11 beta-hydroxysteroid dehydrogenase type 2. The Biochemical journal. 1996;313 ( Pt 3):1007-17. Abstract
Brown P, Scobie GA, Townsend J, Bayne RA, Seckl JR, Saunders PT, et al. Identification of a novel missense mutation that is as damaging to DAX-1 repressor function as a nonsense mutation. The Journal of clinical endocrinology and metabolism. 2003;88:1341-9. Abstract
Brown RW, Chapman KE, Murad P, Edwards CR, Seckl JR. Purification of 11 beta-hydroxysteroid dehydrogenase type 2 from human placenta utilizing a novel affinity labelling technique. Biochem J. 1996;313 ( Pt 3):997-1005. Abstract
Brown RW, Diaz R, Robson AC, Kotelevtsev YV, Mullins JJ, Kaufman MH, et al. The ontogeny of 11 beta-hydroxysteroid dehydrogenase type 2 and mineralocorticoid receptor gene expression reveal intricate control of glucocorticoid action in development. Endocrinology. 1996;137:794-7. Abstract
Bruley C, Lyons V, Worsley AG, Wilde MD, Darlington GD, Morton NM, et al. A novel promoter for the 11beta-hydroxysteroid dehydrogenase type 1 gene is active in lung and is C/EBPalpha independent. Endocrinology. 2006;147:2879-85. Abstract
Brunner EJ, Hemingway H, Walker BR, Page M, Clarke P, Juneja M, et al. Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome: nested case-control study. Circulation. 2002;106:2659-65. Abstract
Brunton PJ, Sullivan KM, Kerrigan D, Russell JA, Seckl JR, Drake AJ. Sex-specific effects of prenatal stress on glucose homeostasis and peripheral metabolism in rats. J Endocrinol. 2013. Abstract
Brunton PJ, Sullivan KM, Kerrigan D, Russell JA, Seckl JR, Drake AJ. Sex-specific effects of prenatal stress on glucose homoeostasis and peripheral metabolism in rats. J Endocrinol. 2013;217(2):161-73. Abstract
Bulling DG, Kelly D, Bond S, McQueen DS, Seckl JR. Adjuvant-induced joint inflammation causes very rapid transcription of beta-preprotachykinin and alpha-CGRP genes in innervating sensory ganglia. Journal of neurochemistry. 2001;77:372-82. Abstract
C
Carter RN, Paterson JM, Tworowska U, Stenvers DJ, Mullins JJ, Seckl JR, et al. Hypothalamic-pituitary-adrenal axis abnormalities in response to deletion of 11beta-HSD1 is strain-dependent. J Neuroendocrinol. 2009;21(11):879-87. Abstract
Chapman KE, Gilmour JS, Coutinho AE, Savill JS, Seckl JR. 11Beta-hydroxysteroid dehydrogenase type 1--a role in inflammation? Mol Cell Endocrinol. 2006;248(1-2):3-8. Abstract
Chapman KE, Kotelevtsev YV, Jamieson PM, Williams LJ, Mullins JJ, Seckl JR. Tissue-specific modulation of glucocorticoid action by the 11 beta-hydroxysteroid dehydrogenases. Biochemical Society transactions. 1997;25:583-7.
Chapman KE, Coutinho A, Gray M, Gilmour JS, Savill JS, Seckl JR. Local amplification of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1 and its role in the inflammatory response. Ann N Y Acad Sci. 2006;1088:265-73. Abstract
Chapman KE, Gilmour JS, Coutinho AE, Savill JS, Seckl JR. 11Beta-hydroxysteroid dehydrogenase type 1–a role in inflammation? Molecular and cellular endocrinology. 2006;248:3-8. Abstract
Chapman KE, Coutinho AE, Gray M, Gilmour JS, Savill JS, Seckl JR. The role and regulation of 11beta-hydroxysteroid dehydrogenase type 1 in the inflammatory response. Mol Cell Endocrinol. 2009;301(1-2):123-31. Abstract
Chapman KE, Seckl JR. 11beta-HSD1, inflammation, metabolic disease and age-related cognitive (dys)function. Neurochem Res. 2008;33(4):624-36. Abstract
Chapman KE, Coutinho A, Gray M, Gilmour JS, Savill JS, Seckl JR. Local amplification of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1 and its role in the inflammatory response. Ann N Y Acad Sci. 2006;1088:265-73. Abstract