Publications

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2013
Dhaun N, Melville V, Blackwell S, Talwar DK, Johnston NR, Goddard J, et al. Endothelin-A receptor antagonism modifies cardiovascular risk factors in CKD. J Am Soc Nephrol. 2013;24(1):31-6. Abstract
2012
Turtle EJ, Dear JW, Webb DJ. A systematic review of the effect of paracetamol on blood pressure in hypertensive and non-hypertensive subjects. Br J Clin Pharmacol. 2012. Abstract
Kirkby NS, Duthie KM, Miller E, Kotelevtsev YV, Bagnall AJ, Webb DJ, et al. Non-endothelial cell endothelin-B receptors limit neointima formation following vascular injury. Cardiovasc Res. 2012;95(1):19-28. Abstract
Lilitkarntakul P, Dhaun N, Melville V, Kerr D, Webb DJ, Goddard J. Risk factors for metabolic syndrome independently predict arterial stiffness and endothelial dysfunction in patients with chronic kidney disease and minimal comorbidity. Diabetes Care. 2012;35(8):1774-80. Abstract
Street JM, Barran PE, Mackay LC, Weidt S, Balmforth C, Walsh TS, et al. Identification and proteomic profiling of exosomes in human cerebrospinal fluid. J Transl Med. 2012;10:5. Abstract
Morrison EE, Turtle EJ, Webb DJ. Observing the NICEties of hypertension management. J R Coll Physicians Edinb. 2012;42(3):251-7. Abstract
2011
Street JM, Birkhoff W, Menzies RI, Webb DJ, Bailey MA, Dear JW. Exosomal transmission of functional aquaporin 2 in kidney cortical collecting duct cells. The Journal of Physiology. 2011. Abstract
Webb DJ. Value-based medicine pricing: NICE work? Lancet. 2011;377(9777):1552-3.
Lilitkarntakul P, Dhaun N, Melville V, Blackwell S, Talwar DK, Liebman B, et al. Blood pressure and not uraemia is the major determinant of arterial stiffness and endothelial dysfunction in patients with chronic kidney disease and minimal co-morbidity. Atherosclerosis. 2011;216(1):217-25. Abstract
Deuchar GA, McLean D, Hadoke PW, Brownstein DG, Webb DJ, Mullins JJ, et al. 11β-hydroxysteroid dehydrogenase type 2 deficiency accelerates atherogenesis and causes proinflammatory changes in the endothelium in apoe-/- mice. Endocrinology. 2011;152(1):236-46. Abstract
Dhaun N, Webb DJ. Dual endothelin-converting enzyme/neutral endopeptidase inhibition: a novel treatment for renovascular hypertension beyond blood pressure lowering? Hypertension. 2011;57(4):667-9.
Dhaun N, Macintyre IM, Kerr D, Melville V, Johnston NR, Haughie S, et al. Selective endothelin-A receptor antagonism reduces proteinuria, blood pressure, and arterial stiffness in chronic proteinuric kidney disease. Hypertension. 2011;57(4):772-9. Abstract
Kirkby NS, Low L, Seckl JR, Walker BR, Webb DJ, Hadoke PW. Quantitative 3-dimensional imaging of murine neointimal and atherosclerotic lesions by optical projection tomography. PLoS ONE. 2011;6(2):e16906. Abstract
2010
Dhaun N, Webb DJ. Receptor tyrosine kinase inhibition, hypertension, and proteinuria: is endothelin the smoking gun? Hypertension. 2010;56(4):575-7.
Webb DJ. DORADO: opportunity postponed: lessons from studies of endothelin receptor antagonists in treatment-resistant hypertension. Hypertension. 2010;56(5):806-7.
Thorin E, Webb DJ. Endothelium-derived endothelin-1. Pflugers Arch. 2010;459(6):951-8. Abstract
Kelland NF, Kuc RE, McLean DL, Azfer A, Bagnall AJ, Gray GA, et al. Endothelial cell-specific ETB receptor knockout: autoradiographic and histological characterisation and crucial role in the clearance of endothelin-1. Can J Physiol Pharmacol. 2010;88(6):644-51. Abstract
Macintyre IM, Dhaun N, Lilitkarntakul P, Melville V, Goddard J, Webb DJ. Greater functional ETB receptor antagonism with bosentan than sitaxsentan in healthy men. Hypertension. 2010;55(6):1406-11. Abstract
Newby DE, Webb DJ. Translational research: a priority for health and wealth. Heart. 2010;96(11):815-6.
Oliver JJ, Dear JW, Webb DJ. Clinical potential of combined organic nitrate and phosphodiesterase type 5 inhibitor in treatment-resistant hypertension. Hypertension. 2010;56(1):62-7. Abstract
Payne RA, Wilkinson IB, Webb DJ. Arterial stiffness and hypertension: emerging concepts. Hypertension. 2010;55(1):9-14.
Payne RA, Lilitkarntakul P, Dhaun N, Melville V, Asai T, Goddard J, et al. Renal dysfunction does not affect the peripheral-to-central arterial pressure transfer function. Hypertension. 2010;56(6):1083-8. Abstract
Kelland NF, Bagnall AJ, Morecroft I, Gulliver-Sloan FH, Dempsie Y, Nilsen M, et al. Endothelial ET(B) limits vascular remodelling and development of pulmonary hypertension during hypoxia. J Vasc Res. 2010;47(1):16-22. Abstract
2009
Dhaun N, Macintyre IM, Melville V, Lilitkarntakul P, Johnston NR, Goddard J, et al. Effects of endothelin receptor antagonism relate to the degree of renin-angiotensin system blockade in chronic proteinuric kidney disease. Hypertension. 2009;54(3):e19-20.
Langrish JP, Lundbäck M, Mills NL, Johnston NR, Webb DJ, Sandström T, et al. Contribution of endothelin 1 to the vascular effects of diesel exhaust inhalation in humans. Hypertension. 2009;54(4):910-5. Abstract