Publications

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1994
Whitworth CE, Fleming S, Cumming AD, Morton JJ, Burns NJ, Williams BC, et al. Spontaneous development of malignant phase hypertension in transgenic Ren-2 rats. Kidney international. 1994;46:1528-32. Abstract
1995
Whitworth CE, Fleming S, Kotelevtsev Y, Manson L, Brooker GA, Cumming AD, et al. A genetic model of malignant phase hypertension in rats. Kidney international. 1995;47:529-35. Abstract
1996
Sharp MG, Fettes D, Brooker G, Clark AF, Peters J, Fleming S, et al. Targeted inactivation of the Ren-2 gene in mice. Hypertension. 1996;28:1126-31. Abstract
1997
Clark AF, Sharp MG, Morley SD, Fleming S, Peters J, Mullins JJ. Renin-1 is essential for normal renal juxtaglomerular cell granulation and macula densa morphology. The Journal of biological chemistry. 1997;272:18185-90. Abstract
1998
Montgomery HE, Kiernan LA, Whitworth CE, Fleming S, Unger T, Gohlke P, et al. Inhibition of tissue angiotensin converting enzyme activity prevents malignant hypertension in TGR(mREN2)27. Journal of hypertension. 1998;16:635-43. Abstract
1999
Kantachuvesiri S, Haley CS, Fleming S, Kurian K, Whitworth CE, Wenham P, et al. Genetic mapping of modifier loci affecting malignant hypertension in TGRmRen2 rats. Kidney international. 1999;56:414-20. Abstract
Kotelevtsev Y, Brown RW, Fleming S, Kenyon C, Edwards CR, Seckl JR, et al. Hypertension in mice lacking 11beta-hydroxysteroid dehydrogenase type 2. The Journal of clinical investigation. 1999;103:683-9. Abstract
2000
Mullins LJ, Payne CM, Kotelevtseva N, Brooker G, Fleming S, Harris S, et al. Granulation rescue and developmental marking of juxtaglomerular cells using "piggy-BAC" recombination of the mouse ren locus. The Journal of biological chemistry. 2000;275:40378-84. Abstract
2001
Kantachuvesiri S, Fleming S, Peters J, Peters B, Brooker G, Lammie AG, et al. Controlled hypertension, a transgenic toggle switch reveals differential mechanisms underlying vascular disease. The Journal of biological chemistry. 2001;276:36727-33. Abstract
2002
Mayer NJ, Forsyth A, Kantachuvesiri S, Mullins JJ, Fleming S. Association of the D allele of the angiotensin I converting enzyme polymorphism with malignant vascular injury. Molecular pathology : MP. 2002;55:29-33. Abstract