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B
Barron RM, Campbell SL, King D, Bellon A, Chapman KE, Williamson AR, et al. High titers of transmissible spongiform encephalopathy infectivity associated with extremely low levels of PrPSc in vivo. J Biol Chem. 2007;282(49):35878-86. Abstract
Brown RW, Chapman KE, Murad P, Edwards CR, Seckl JR. Purification of 11 beta-hydroxysteroid dehydrogenase type 2 from human placenta utilizing a novel affinity labelling technique. Biochem J. 1996;313 ( Pt 3):997-1005. Abstract
Brown RW, Chapman KE, Edwards CR, Seckl JR. Human placental 11 beta-hydroxysteroid dehydrogenase: evidence for and partial purification of a distinct NAD-dependent isoform. Endocrinology. 1993;132(6):2614-21. Abstract
Brown RW, Chapman KE, Kotelevtsev Y, Yau JL, Lindsay RS, Brett L, et al. Cloning and production of antisera to human placental 11 beta-hydroxysteroid dehydrogenase type 2. The Biochemical journal. 1996;313 ( Pt 3):1007-17. Abstract
Bruley C, Lyons V, Worsley AG, Wilde MD, Darlington GD, Morton NM, et al. A novel promoter for the 11beta-hydroxysteroid dehydrogenase type 1 gene is active in lung and is C/EBPalpha independent. Endocrinology. 2006;147:2879-85. Abstract
Bujalska IJ, Draper N, Michailidou Z, Tomlinson JW, White PC, Chapman KE, et al. Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydroxysteroid dehydrogenase type 1. J Mol Endocrinol. 2005;34(3):675-84. Abstract
Bujalska IJ, Draper N, Michailidou Z, Tomlinson JW, White PC, Chapman KE, et al. Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydroxysteroid dehydrogenase type 1. Journal of molecular endocrinology. 2005;34:675-84. Abstract
C
Chapman KE, Seckl JR. 11beta-HSD1, inflammation, metabolic disease and age-related cognitive (dys)function. Neurochem Res. 2008;33(4):624-36. Abstract
Chapman KE, Coutinho A, Gray M, Gilmour JS, Savill JS, Seckl JR. Local amplification of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1 and its role in the inflammatory response. Ann N Y Acad Sci. 2006;1088:265-73. Abstract
Chapman KE, Coutinho AE, Gray M, Gilmour JS, Savill JS, Seckl JR. The role and regulation of 11beta-hydroxysteroid dehydrogenase type 1 in the inflammatory response. Mol Cell Endocrinol. 2009;301(1-2):123-31. Abstract
Chapman KE, Odermatt A. Steroids: Modulators of inflammation and immunity. J Steroid Biochem Mol Biol. 2010;120(2-3):67-8.
Chapman KE, Kotelevtsev YV, Jamieson PM, Williams LJ, Mullins JJ, Seckl JR. Tissue-specific modulation of glucocorticoid action by the 11 beta-hydroxysteroid dehydrogenases. Biochemical Society transactions. 1997;25:583-7.
Chapman KE, Gilmour JS, Coutinho AE, Savill JS, Seckl JR. 11Beta-hydroxysteroid dehydrogenase type 1–a role in inflammation? Molecular and cellular endocrinology. 2006;248:3-8. Abstract
Chapman KE, Coutinho AE, Gray M, Gilmour JS, Savill JS, Seckl JR. The role and regulation of 11beta-hydroxysteroid dehydrogenase type 1 in the inflammatory response. Mol Cell Endocrinol. 2009;301(1-2):123-31. Abstract
Chapman KE, Coutinho A, Gray M, Gilmour JS, Savill JS, Seckl JR. Local amplification of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1 and its role in the inflammatory response. Ann N Y Acad Sci. 2006;1088:265-73. Abstract
Chapman KE, Gilmour JS, Coutinho AE, Savill JS, Seckl JR. 11Beta-hydroxysteroid dehydrogenase type 1--a role in inflammation? Mol Cell Endocrinol. 2006;248(1-2):3-8. Abstract
Coutinho AE, Gray M, Brownstein DG, Salter DM, Sawatzky DA, Clay S, et al. 11β-Hydroxysteroid dehydrogenase type 1, but not type 2, deficiency worsens acute inflammation and experimental arthritis in mice. Endocrinology. 2012;153(1):234-40. Abstract
Coutinho AE, Chapman KE. The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights. Mol Cell Endocrinol. 2010. Abstract
Coutinho AE, Chapman KE. The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights. Mol Cell Endocrinol. 2011;335(1):2-13. Abstract
D
De Sousa Peixoto RA, Turban S, Battle JH, Chapman KE, Seckl JR, Morton NM. Preadipocyte 11beta-hydroxysteroid dehydrogenase type 1 is a keto-reductase and contributes to diet-induced visceral obesity in vivo. Endocrinology. 2008;149(4):1861-8. Abstract
De Sousa Peixoto RA, Turban S, Battle JH, Chapman KE, Seckl JR, Morton NM. Preadipocyte 11beta-hydroxysteroid dehydrogenase type 1 is a keto-reductase and contributes to diet-induced visceral obesity in vivo. Endocrinology. 2008;149(4):1861-8. Abstract
Deary IJ, Hayward C, Permana PA, Nair S, Whalley LJ, Starr JM, et al. Polymorphisms in the gene encoding 11B-hydroxysteroid dehydrogenase type 1 (HSD11B1) and lifetime cognitive change. Neuroscience letters. 2006;393:74-7. Abstract
Deuchar GA, McLean D, Hadoke PW, Brownstein DG, Webb DJ, Mullins JJ, et al. 11β-hydroxysteroid dehydrogenase type 2 deficiency accelerates atherogenesis and causes proinflammatory changes in the endothelium in apoe-/- mice. Endocrinology. 2011;152(1):236-46. Abstract
E
Esteves CL, Kelly V, Bégay V, Man TY, Morton NM, Leutz A, et al. Regulation of adipocyte 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) by CCAAT/enhancer-binding protein (C/EBP) β isoforms, LIP and LAP. PLoS ONE. 2012;7(5):e37953. Abstract
F
Freeman AI, Munn HL, Lyons V, Dammermann A, Seckl JR, Chapman KE. Glucocorticoid down-regulation of rat glucocorticoid receptor does not involve differential promoter regulation. The Journal of endocrinology. 2004;183:365-74. Abstract