Publications

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Densmore VS, Morton NM, Mullins JJ, Seckl JR. 11 beta-hydroxysteroid dehydrogenase type 1 induction in the arcuate nucleus by high-fat feeding: A novel constraint to hyperphagia? Endocrinology. 2006;147:4486-95. Abstract
Holmes MC, Yau JL, Kotelevtsev Y, Mullins JJ, Seckl JR. 11 Beta-hydroxysteroid dehydrogenases in the brain: two enzymes two roles. Annals of the New York Academy of Sciences. 2003;1007:357-66. Abstract
Holmes MC, Carter RN, Noble J, Chitnis S, Dutia A, Paterson JM, et al. 11beta-hydroxysteroid dehydrogenase type 1 expression is increased in the aged mouse hippocampus and parietal cortex and causes memory impairments. J Neurosci. 2010;30(20):6916-20. Abstract
Kotelevtsev Y, Holmes MC, Burchell A, Houston PM, Schmoll D, Jamieson P, et al. 11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress. Proceedings of the National Academy of Sciences of the United States of America. 1997;94:14924-9. Abstract
Christy C, Hadoke PW, Paterson JM, Mullins JJ, Seckl JR, Walker BR. 11beta-hydroxysteroid dehydrogenase type 2 in mouse aorta: localization and influence on response to glucocorticoids. Hypertension. 2003;42:580-7. Abstract
Holmes MC, Sangra M, French KL, Whittle IR, Paterson J, Mullins JJ, et al. 11beta-Hydroxysteroid dehydrogenase type 2 protects the neonatal cerebellum from deleterious effects of glucocorticoids. Neuroscience. 2006;137:865-73. Abstract
Deuchar GA, McLean D, Hadoke PW, Brownstein DG, Webb DJ, Mullins JJ, et al. 11β-hydroxysteroid dehydrogenase type 2 deficiency accelerates atherogenesis and causes proinflammatory changes in the endothelium in apoe-/- mice. Endocrinology. 2011;152(1):236-46. Abstract
A
Ashek A, Menzies RI, Mullins LJ, Bellamy CO, Harmar AJ, Kenyon CJ, et al. Activation of Thiazide-Sensitive Co-Transport by Angiotensin II in the cyp1a1-Ren2 Hypertensive Rat. PLoS ONE. 2012;7(4):e36311. Abstract
Morley SD, Viard I, Parker KL, Mullins JJ. Adrenal-specific transgene expression and derivation of conditionally immortal rat adrenocortical cell lines. Endocrine research. 1995;21:353-7. Abstract
Morley SD, Viard I, Parker KL, Mullins JJ. Adrenocortical-specific transgene expression directed by steroid hydroxylase gene promoters. Endocrine research. 1996;22:631-9. Abstract
Ortiz RM, Graciano ML, Mullins JJ, Mitchell KD. Aldosterone receptor antagonism alleviates proteinuria, but not malignant hypertension, in Cyp1a1-Ren2 transgenic rats. American journal of physiology. Renal physiology. 2007;293:F1584-91. Abstract
Ye P, Kenyon CJ, MacKenzie SM, Jong AS, Miller C, Gray GA, et al. The aldosterone synthase (CYP11B2) and 11beta-hydroxylase (CYP11B1) genes are not expressed in the rat heart. Endocrinology. 2005;146:5287-93. Abstract
Fabian JR, Field LJ, McGowan RA, Mullins JJ, Sigmund CD, Gross KW. Allele-specific expression of the murine Ren-1 genes. The Journal of biological chemistry. 1989;264:17589-94. Abstract
Heerkens EH, Shaw L, Ryding A, Brooker G, Mullins JJ, Austin C, et al. alphaV integrins are necessary for eutrophic inward remodeling of small arteries in hypertension. Hypertension. 2006;47(2):281-7. Abstract
Mitchell KD, Mullins JJ. ANG II dependence of tubuloglomerular feedback responsiveness in hypertensive ren-2 transgenic rats. The American journal of physiology. 1995;268:F821-8. Abstract
Liu X, Bellamy CO, Bailey MA, Mullins LJ, Dunbar DR, Kenyon CJ, et al. Angiotensin-converting enzyme is a modifier of hypertensive end organ damage. The Journal of biological chemistry. 2009;284:15564-72. Abstract
Mayer NJ, Forsyth A, Kantachuvesiri S, Mullins JJ, Fleming S. Association of the D allele of the angiotensin I converting enzyme polymorphism with malignant vascular injury. Molecular pathology : MP. 2002;55:29-33. Abstract
Vanourková Z, Kramer HJ, Husková Z, Vanecková I, Opocenský M, Chábová VC, et al. AT1 receptor blockade is superior to conventional triple therapy in protecting against end-organ damage in Cyp1a1-Ren-2 transgenic rats with inducible hypertension. J Hypertens. 2006;24(12):2465-72. Abstract
Williams DE, Prieto MC, Mullins JJ, Navar GL, Mitchell KD. AT1 receptor blockade prevents the increase in blood pressure and the augmentation of intrarenal ANG II levels in hypertensive Cyp1a1-Ren2 transgenic rats fed with a high-salt diet. Am J Med Sci. 2010;339(4):356-61. Abstract
Manning JR, Hedley A, Mullins JJ, Dunbar DR. Automated seeding of specialised wiki knowledgebases with BioKb. BMC bioinformatics. 2009;10:291. Abstract
Bunnemann B, Fuxe K, Metzger R, Mullins J, Jackson TR, Hanley MR, et al. Autoradiographic localization of mas proto-oncogene mRNA in adult rat brain using in situ hybridization. Neuroscience letters. 1990;114:147-53. Abstract
B
Catanzaro DF, Mullins JJ, Morris BJ. The biosynthetic pathway of renin in mouse submandibular gland. The Journal of biological chemistry. 1983;258:7364-8. Abstract
C
Ratty AK, Fitzgerald LW, Titeler M, Glick SD, Mullins JJ, Gross KW. Circling behavior exhibited by a transgenic insertional mutant. Brain research. Molecular brain research. 1990;8:355-8. Abstract
Brown SB, Tucker CS, Ford C, Lee Y, Dunbar DR, Mullins JJ. Class III antiarrhythmic methanesulfonanilides inhibit leukocyte recruitment in zebrafish. Journal of leukocyte biology. 2007;82:79-84. Abstract
Brown RW, Chapman KE, Kotelevtsev Y, Yau JL, Lindsay RS, Brett L, et al. Cloning and production of antisera to human placental 11 beta-hydroxysteroid dehydrogenase type 2. The Biochemical journal. 1996;313 ( Pt 3):1007-17. Abstract