Publications

Export 14 results:
Sort by: [ Author (Desc)] Title Type Year
Filters: Author is Brown, C M  [Clear All Filters]
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 
R
Redfern WS, Mackinnon AC, Brown CM, Martin AB, Kilpatrick AT, Clague RU, et al. Modulation of central noradrenergic function by RS-15385-197. Br J Pharmacol. 1993;108(2):526-33. Abstract
M
Mackinnon AC, Brown CM, Spedding M, Kilpatrick AT. [3H]-idazoxan binds with high affinity to two sites on hamster adipocytes: an alpha 2-adrenoceptor and a non-adrenoceptor site. Br J Pharmacol. 1989;98(4):1143-50. Abstract
Mackinnon AC, Kilpatrick AT, Kenny BA, Spedding M, Brown CM. [3H]-RS-15385-197, a selective and high affinity radioligand for alpha 2-adrenoceptors: implications for receptor classification. Br J Pharmacol. 1992;106(4):1011-8. Abstract
Mackinnon AC, Spedding M, Brown CM. Sodium modulation of 3H-agonist and 3H-antagonist binding to alpha 2-adrenoceptor subtypes. Br J Pharmacol. 1993;109(2):371-8. Abstract
Mackinnon AC, Spedding M, Brown CM. Alpha 2-adrenoceptors: more subtypes but fewer functional differences. Trends Pharmacol Sci. 1994;15(4):119-23. Abstract
K
Kilpatrick AT, Brown CM, Mackinnon AC, Spedding M. The alpha 2-adrenoceptor antagonist SK&F 104078 has high affinity for 5-HT1A and 5-HT2 receptors. Eur J Pharmacol. 1989;166(2):315-8. Abstract
Kenny BA, Mackinnon AC, Spedding M, Brown CM. Changes in [3H]-PK 11195 and [3H]-8-OH-DPAT binding following forebrain ischaemia in the gerbil. Br J Pharmacol. 1993;109(2):437-42. Abstract
C
Clark RD, Repke DB, Kilpatrick AT, Brown CM, Mackinnon AC, Clague RU, et al. (8a alpha,12a alpha,13a alpha)-5,8,8a,9,10,11,12,12a,13,13a-decahydro- 3-methoxy-12-(methylsulfonyl)-6H-isoquino[2,1-g][1,6]naphthyridi ne, a potent and highly selective alpha 2-adrenoceptor antagonist. J Med Chem. 1989;32(9):2034-6.
Clark RD, Weinhardt KK, Berger J, Fisher LE, Brown CM, Mackinnon AC, et al. 1,9-Alkano-bridged 2,3,4,5-tetrahydro-1H-3-benzazepines with affinity for the alpha 2-adrenoceptor and the 5-HT1A receptor. J Med Chem. 1990;33(2):633-41. Abstract
Clark RD, Repke DB, Berger J, Nelson JT, Kilpatrick AT, Brown CM, et al. Structure-affinity relationships of 12-sulfonyl derivatives of 5,8,8a,9,10,11,12,12a,13,13a-decahydro-6H-isoquino[2,1-g][1 ,6] naphthyridines at alpha-adrenoceptors. J Med Chem. 1991;34(2):705-17. Abstract
Clark RD, Berger J, Garg P, Weinhardt KK, Spedding M, Kilpatrick AT, et al. Affinity of 2-(tetrahydroisoquinolin-2-ylmethyl)- and 2-(isoindolin-2-ylmethyl)imidazolines for alpha-adrenoceptors. Differential affinity of imidazolines for the [3H]idazoxan-labeled alpha 2-adrenoceptor vs the [3H]yohimbine-labeled site. J Med Chem. 1990;33(2):596-600. Abstract
B
Brown CM, Mackinnon AC, McGrath JC, Spedding M, Kilpatrick AT. Heterogeneity of alpha 2-adrenoceptors in rat cortex but not human platelets can be defined by 8-OH-DPAT, RU 24969 and methysergide. Br J Pharmacol. 1990;99(3):481-6. Abstract
Brown CM, Mackinnon AC, Redfern WS, Williams A, Linton C, Stewart M, et al. RS-45041-190: a selective, high-affinity ligand for I2 imidazoline receptors. Br J Pharmacol. 1995;116(2):1737-44. Abstract
Brown CM, Mackinnon AC, McGrath JC, Spedding M, Kilpatrick AT. Alpha 2-adrenoceptor subtypes and imidazoline-like binding sites in the rat brain. Br J Pharmacol. 1990;99(4):803-9. Abstract