Publications

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2013
Sharman JL, Benson HE, Pawson AJ, Lukito V, Mpamhanga CP, Bombail V, et al. IUPHAR-DB: updated database content and new features. Nucleic Acids Res. 2013;41(Database Issue):8. Abstract
2012
Tracey CJ, Pan X, Catterson JH, Harmar AJ, Hussain MM, Hartley PS. Diurnal expression of Thrombopoietin is regulated by Clock. Journal of Thrombosis and Haemostasis. 2012.
Alexander SP, Benson HE, Davenport A, Mathie A, McGrath IJ, Pawson AJ, et al. GuideToPharmacology.org - an update. Br J Pharmacol. 2012;167(4):697-8.
Harmar AJ, Fahrenkrug J, Gozes I, Laburthe M, May V, Pisegna JR, et al. Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide: IUPHAR Review 1. British journal of pharmacology. 2012;166(1):4-17. Abstract
Ashek A, Menzies RI, Mullins LJ, Bellamy CO, Harmar AJ, Kenyon CJ, et al. Activation of Thiazide-Sensitive Co-Transport by Angiotensin II in the cyp1a1-Ren2 Hypertensive Rat. PLoS ONE. 2012;7(4):e36311. Abstract
Mpamhanga CP, Sharman JL, Harmar AJ. How to Use the IUPHAR Receptor Database to Navigate Pharmacological Data.. In: Methods in molecular biology (Clifton, N.J.). Vol 897.; 2012. p. 15-29. (Methods Mol Biol; vol 897). Abstract
2011
Sharman JL, Mpamhanga CP, Spedding M, Germain P, Staels B, Dacquet C, et al. IUPHAR-DB: new receptors and tools for easy searching and visualization of pharmacological data. Nucleic Acids Res. 2011;39(Database issue):D534-8. Abstract
2010
Sheward JW, Naylor E, Knowles-Barley S, Armstrong DJ, Brooker GA, Seckl JR, et al. Circadian control of mouse heart rate and blood pressure by the suprachiasmatic nuclei: behavioral effects are more significant than direct outputs. PloS one. 2010;5:e9783. Abstract
Catterson JH, Knowles-Barley S, James K, Heck MM, Harmar AJ, Hartley PS. Dietary modulation of Drosophila sleep-wake behaviour. PLoS ONE. 2010;5(8):e12062. Abstract
Harmar AJ. What therapeutic opportunities are afforded by increasing our understanding of central and peripheral clocks? Dialogues in Cardiovascular Medicine. 2010;15(1):36-42. Abstract
2009
Zaben M, Sheward JW, Shtaya A, Abbosh C, Harmar AJ, Pringle AK, et al. The neurotransmitter VIP expands the pool of symmetrically dividing postnatal dentate gyrus precursors via VPAC2 receptors or directs them toward a neuronal fate via VPAC1 receptors. Stem Cells. 2009;27(10):2539-51. Abstract
Hartley PS, Sheward J, Scholefield E, French K, Horn JM, Holmes MC, et al. Timed feeding of mice modulates light-entrained circadian rhythms of reticulated platelet abundance and plasma thrombopoietin and affects gene expression in megakaryocytes. British journal of haematology. 2009;146:185-92. Abstract
Harmar AJ, Hills RA, Rosser EM, Jones M, Buneman PO, Dunbar DR, et al. IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels. Nucleic acids research. 2009;37:D680-5. Abstract
Dawson N, Ferrington L, Olverman HJ, Harmar AJ, Kelly PA. Sex influences the effect of a lifelong increase in serotonin transporter function on cerebral metabolism. J Neurosci Res. 2009;87(10):2375-85. Abstract
2008
Dempsie Y, Morecroft I, Welsh DJ, MacRitchie NA, Herold N, Loughlin L, et al. Converging evidence in support of the serotonin hypothesis of dexfenfluramine-induced pulmonary hypertension with novel transgenic mice. Circulation. 2008;117(22):2928-37. Abstract
Dempsie Y, Morecroft I, Welsh DJ, MacRitchie NA, Herold N, Loughlin L, et al. Converging evidence in support of the serotonin hypothesis of dexfenfluramine-induced pulmonary hypertension with novel transgenic mice. Circulation. 2008;117(22):2928-37. Abstract
Hartley PS, John Sheward W, French K, Horn JM, Holmes MC, Harmar AJ. Food-entrained rhythmic expression of PER2 and BMAL1 in murine megakaryocytes does not correlate with circadian rhythms in megakaryopoiesis. Journal of thrombosis and haemostasis : JTH. 2008;6:1144-52. Abstract
Jennings KA, Sheward WJ, Harmar AJ, Sharp T. Evidence that genetic variation in 5-HT transporter expression is linked to changes in 5-HT2A receptor function. Neuropharmacology. 2008;54:776-83. Abstract
Jennings KA, Sheward WJ, Harmar AJ, Sharp T. Evidence that genetic variation in 5-HT transporter expression is linked to changes in 5-HT2A receptor function. Neuropharmacology. 2008;54(5):776-83. Abstract
2007
Sheward JW, Maywood ES, French KL, Horn JM, Hastings MH, Seckl JR, et al. Entrainment to feeding but not to light: circadian phenotype of VPAC2 receptor-null mice. J Neurosci. 2007;27(16):4351-8. Abstract
2006
Maywood ES, Reddy AB, Wong GK, O'Neill JS, O'Brien JA, McMahon DG, et al. Synchronization and maintenance of timekeeping in suprachiasmatic circadian clock cells by neuropeptidergic signaling. Curr Biol. 2006;16(6):599-605. Abstract
Lang B, Song B, Davidson W, MacKenzie A, Smith N, McCaig CD, et al. Expression of the human PAC1 receptor leads to dose-dependent hydrocephalus-related abnormalities in mice. The Journal of clinical investigation. 2006;116:1924-34. Abstract
Jennings KA, Loder MK, Sheward JW, Pei Q, Deacon RM, Benson MA, et al. Increased expression of the 5-HT transporter confers a low-anxiety phenotype linked to decreased 5-HT transmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2006;26:8955-64. Abstract
Pakhotin P, Harmar AJ, Verkhratsky A, Piggins H. VIP receptors control excitability of suprachiasmatic nuclei neurones. Pflügers Archiv : European journal of physiology. 2006;452:7-15. Abstract
2005
Foord SM, Bonner TI, Neubig RR, Rosser EM, Pin J-, Davenport AP, et al. International Union of Pharmacology. XLVI. G protein-coupled receptor list. Pharmacological reviews. 2005;57:279-88. Abstract