Publications

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2013
Reynolds RM, Jacobsen GH, Drake AJ. What is the evidence in humans that DNA methylation changes link events in utero and later life disease? Clin Endocrinol (Oxf). 2013. Abstract
Brunton PJ, Sullivan KM, Kerrigan D, Russell JA, Seckl JR, Drake AJ. Sex-specific effects of prenatal stress on glucose homoeostasis and peripheral metabolism in rats. J Endocrinol. 2013;217(2):161-73. Abstract
Sharpe RM, Drake AJ. Obesogens and obesity: An alternative view. Obesity. 2013.
2012
Khulan B, Drake AJ. Glucocorticoids as mediators of developmental programming effects. Best Pract Res Clin Endocrinol Metab. 2012;26(5):689-700. Abstract
Wyrwoll CS, Kerrigan D, Holmes MC, Seckl JR, Drake AJ. Altered placental methyl donor transport in the dexamethasone programmed rat. Placenta. 2012;33(3):220-3. Abstract
Tyndall V, Broyde M, Sharpe R, Welsh M, Drake AJ, McNeilly AS. Effect of androgen treatment during foetal and/or neonatal life on ovarian function in prepubertal and adult rats. Reproduction. 2012;143(1):21-33. Abstract
Drake AJ, McPherson RC, Godfrey KM, Cooper C, Lillycrop KA, Hanson MA, et al. An unbalanced maternal diet in pregnancy associates with offspring epigenetic changes in genes controlling glucocorticoid action and foetal growth. Clin Endocrinol (Oxf). 2012;77(6):808-15. Abstract
van den Driesche S, Kolovos P, Platts S, Drake AJ, Sharpe RM. Inter-Relationship between Testicular Dysgenesis and Leydig Cell Function in the Masculinization Programming Window in the Rat. PLoS ONE. 2012;7(1):e30111. Abstract
van den Driesche S, Walker M, McKinnell C, Scott HM, Eddie SL, Mitchell RT, et al. Proposed Role for COUP-TFII in Regulating Fetal Leydig Cell Steroidogenesis, Perturbation of Which Leads to Masculinization Disorders in Rodents. PLoS ONE. 2012;7(5):e37064. Abstract
2011
Fowler PA, Bhattacharya S, Flannigan S, Drake AJ, O'Shaughnessy PJ. Maternal cigarette smoking and effects on androgen action in male offspring: unexpected effects on second-trimester anogenital distance. J Clin Endocrinol Metab. 2011;96(9):E1502-6. Abstract
Drake AJ, Liu L, Kerrigan D, Meehan RR, Seckl JR. Multigenerational programming in the glucocorticoid programmed rat is associated with generation-specific and parent of origin effects. Epigenetics. 2011;6(11). Abstract
Drake AJ, Seckl JR. Transmission of programming effects across generations. Pediatr Endocrinol Rev. 2011;9(2):566-78. Abstract
2010
Drake AJ, Reynolds RM. Impact of maternal obesity on offspring obesity and cardiometabolic disease risk. Reproduction. 2010;140(3):387-98. Abstract
Khadr SN, Crofton PM, Jones PA, Wardhaugh B, Roach J, Drake AJ, et al. Evaluation of pituitary function after traumatic brain injury in childhood. Clin Endocrinol (Oxf). 2010;73(5):637-43. Abstract
Sharpe RM, Drake AJ. Bisphenol a and metabolic syndrome. Endocrinology. 2010;151(6):2404-7.
Macleod DJ, Sharpe RM, Welsh M, Fisken M, Scott HM, Hutchison GR, et al. Androgen action in the masculinization programming window and development of male reproductive organs. Int J Androl. 2010;33(2):279-87. Abstract
Drake AJ, Liu L. Intergenerational transmission of programmed effects: public health consequences. Trends Endocrinol Metab. 2010;21(4):206-13. Abstract
Drake AJ, Raubenheimer PJ, Kerrigan D, McInnes KJ, Seckl JR, Walker BR. Prenatal dexamethasone programs expression of genes in liver and adipose tissue and increased hepatic lipid accumulation but not obesity on a high-fat diet. Endocrinology. 2010;151(4):1581-7. Abstract
2009
Drake AJ, van den Driesche S, Scott HM, Hutchison GR, Seckl JR, Sharpe RM. Glucocorticoids amplify dibutyl phthalate-induced disruption of testosterone production and male reproductive development. Endocrinology. 2009;150:5055-64. Abstract
Drake AJ, van den Driesche S, Scott HM, Hutchison GR, Seckl JR, Sharpe RM. Glucocorticoids amplify dibutyl phthalate-induced disruption of testosterone production and male reproductive development. Endocrinology. 2009;150(11):5055-64. Abstract
2008
Scott HM, Hutchison GR, Jobling MS, McKinnell C, Drake AJ, Sharpe RM. Relationship between androgen action in the "male programming window," fetal sertoli cell number, and adult testis size in the rat. Endocrinology. 2008;149:5280-7. Abstract
2005
Drake AJ, Walker BR, Seckl JR. Intergenerational consequences of fetal programming by in utero exposure to glucocorticoids in rats. American journal of physiology. Regulatory, integrative and comparative physiology. 2005;288:R34-8. Abstract
Drake AJ, Livingstone DE, Andrew R, Seckl JR, Morton NM, Walker BR. Reduced adipose glucocorticoid reactivation and increased hepatic glucocorticoid clearance as an early adaptation to high-fat feeding in Wistar rats. Endocrinology. 2005;146:913-9. Abstract
2004
Drake AJ, Walker BR. The intergenerational effects of fetal programming: non-genomic mechanisms for the inheritance of low birth weight and cardiovascular risk. The Journal of endocrinology. 2004;180:1-16. Abstract
2002
Drake AJ, Howells RJ, Shield JP, Prendiville A, Ward PS, Crowne EC. Symptomatic adrenal insufficiency presenting with hypoglycaemia in children with asthma receiving high dose inhaled fluticasone propionate. BMJ. 2002;324(7345):1081-2.