Publications

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Zhao Y, Bader M, Kreutz R, Fernandez-Alfonso M, Zimmermann F, Ganten U, et al. Ontogenetic regulation of mouse Ren-2d renin gene in transgenic hypertensive rats, TGR(mREN2)27. The American journal of physiology. 1993;265:E699-707. Abstract
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Ye P, Kenyon CJ, MacKenzie SM, Jong AS, Miller C, Gray GA, et al. The aldosterone synthase (CYP11B2) and 11beta-hydroxylase (CYP11B1) genes are not expressed in the rat heart. Endocrinology. 2005;146:5287-93. Abstract
Yau JL, Noble J, Kenyon CJ, Hibberd C, Kotelevtsev Y, Mullins JJ, et al. Lack of tissue glucocorticoid reactivation in 11beta -hydroxysteroid dehydrogenase type 1 knockout mice ameliorates age-related learning impairments. Proceedings of the National Academy of Sciences of the United States of America. 2001;98:4716-21. Abstract
Yau JL, McNair KM, Noble J, Brownstein D, Hibberd C, Morton N, et al. Enhanced hippocampal long-term potentiation and spatial learning in aged 11beta-hydroxysteroid dehydrogenase type 1 knock-out mice. J Neurosci. 2007;27(39):10487-96. Abstract
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Windass JD, Mullins JJ, Beecroft LJ, George H, Meacock PA, Williams BR, et al. Molecular cloning of cDNAs from androgen-independent mRNA species of DBA/2 mouse sub-maxillary glands. Nucleic acids research. 1984;12:1361-76. Abstract
Williams DE, Prieto MC, Mullins JJ, Navar GL, Mitchell KD. AT1 receptor blockade prevents the increase in blood pressure and the augmentation of intrarenal ANG II levels in hypertensive Cyp1a1-Ren2 transgenic rats fed with a high-salt diet. Am J Med Sci. 2010;339(4):356-61. Abstract
Whitworth CE, Veniant MM, Firth JD, Cumming AD, Mullins JJ. Endothelin in the kidney in malignant phase hypertension. Hypertension. 1995;26:925-31. Abstract
Whitworth CE, Fleming S, Cumming AD, Morton JJ, Burns NJ, Williams BC, et al. Spontaneous development of malignant phase hypertension in transgenic Ren-2 rats. Kidney international. 1994;46:1528-32. Abstract
Whitworth CE, Fleming S, Kotelevtsev Y, Manson L, Brooker GA, Cumming AD, et al. A genetic model of malignant phase hypertension in rats. Kidney international. 1995;47:529-35. Abstract
Wagner J, Jan Danser AH, Derkx FH, de Jong TV, Paul M, Mullins JJ, et al. Demonstration of renin mRNA, angiotensinogen mRNA, and angiotensin converting enzyme mRNA expression in the human eye: evidence for an intraocular renin-angiotensin system. The British journal of ophthalmology. 1996;80:159-63. Abstract
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Véniant M, Ménard J, Bruneval P, Morley S, Gonzales MF, Mullins J. Vascular damage without hypertension in transgenic rats expressing prorenin exclusively in the liver. The Journal of clinical investigation. 1996;98:1966-70. Abstract
Véniant M, Whitworth CE, Ménard J, Sharp MG, Gonzales MF, Bruneval P, et al. Developmental studies demonstrate age-dependent elevation of renin activity in TGR(mRen2)27 rats. American journal of hypertension. 1995;8:1167-76. Abstract
Vanourková Z, Kramer HJ, Husková Z, Vanecková I, Opocenský M, Chábová VC, et al. AT1 receptor blockade is superior to conventional triple therapy in protecting against end-organ damage in Cyp1a1-Ren-2 transgenic rats with inducible hypertension. J Hypertens. 2006;24(12):2465-72. Abstract
Van Agtmael T, Schlötzer-Schrehardt U, McKie L, Brownstein DG, Lee AW, Cross SH, et al. Dominant mutations of Col4a1 result in basement membrane defects which lead to anterior segment dysgenesis and glomerulopathy. Human molecular genetics. 2005;14:3161-8. Abstract
Van Agtmael T, Bailey MA, Schlötzer-Schrehardt U, Craigie E, Jackson IJ, Brownstein DG, et al. Col4a1 mutation in mice causes defects in vascular function and low blood pressure associated with reduced red blood cell volume. Human molecular genetics. 2010;19:1119-28. Abstract
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Unger T, Ganten D, Johnston CI, Lever AF, Mullins JJ, Sassard J, et al. Round table 1. Do transgenic techniques help us to understand hypertension? Journal of hypertension. Supplement : official journal of the International Society of Hypertension. 1993;11:S374-9.
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Turban S, Liu X, Ramage L, Webster SP, Walker BR, Dunbar DR, et al. Optimal Elevation of β-Cell 11β-Hydroxysteroid Dehydrogenase Type 1 Is a Compensatory Mechanism that Prevents High Fat Diet-Induced β-Cell Failure. Diabetes. 2012. Abstract
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Sigmund CD, Jones CA, Fabian JR, Mullins JJ, Gross KW. Tissue and cell specific expression of a renin promoter-reporter gene construct in transgenic mice. Biochemical and biophysical research communications. 1990;170:344-50. Abstract
Sigmund CD, Jones CA, Mullins JJ, Kim U, Gross KW. Expression of murine renin genes in subcutaneous connective tissue. Proceedings of the National Academy of Sciences of the United States of America. 1990;87:7993-7. Abstract
Sigmund CD, Okuyama K, Ingelfinger J, Jones CA, Mullins JJ, Kane C, et al. Isolation and characterization of renin-expressing cell lines from transgenic mice containing a renin-promoter viral oncogene fusion construct. The Journal of biological chemistry. 1990;265:19916-22. Abstract
Sharpe RM, Maguire SM, Saunders PT, Millar MR, Russell LD, Ganten D, et al. Infertility in a transgenic rat due to impairment of cytoplasmic elimination and sperm release from the Sertoli cells. Biology of reproduction. 1995;53:214-26. Abstract
Sharp MG, Kantachuvesiri S, Mullins JJ. Genotype and cardiovascular phenotype: lessons from genetically manipulated animals and diseased humans. Current opinion in nephrology and hypertension. 1997;6:51-7. Abstract
Sharp MG, Fettes D, Brooker G, Clark AF, Peters J, Fleming S, et al. Targeted inactivation of the Ren-2 gene in mice. Hypertension. 1996;28:1126-31. Abstract
Sharp MG, Mullins JJ. Loss of gene function methodology. Journal of hypertension. 1993;11:339-43.
Semprini S, McNamara AV, Awais R, Featherstone K, Harper CV, McNeilly JR, et al. Peritonitis Activates Transcription of the Human Prolactin Locus in Myeloid Cells in a Humanized Transgenic Rat Model. Endocrinology. 2012. Abstract