<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Denison, F C</style></author><author><style face="normal" font="default" size="100%">Norrie, G</style></author><author><style face="normal" font="default" size="100%">Graham, B</style></author><author><style face="normal" font="default" size="100%">Lynch, J</style></author><author><style face="normal" font="default" size="100%">Harper, N</style></author><author><style face="normal" font="default" size="100%">Reynolds, R M</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Increased maternal BMI is associated with an increased risk of minor complications during pregnancy with consequent cost implications.</style></title><secondary-title><style face="normal" font="default" size="100%">BJOG : an international journal of obstetrics and gynaecology</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2009</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2009 Oct</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">116</style></volume><pages><style face="normal" font="default" size="100%">1467-72</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">OBJECTIVE: To investigate the effect of maternal body mass index (BMI) on minor complications, associated additional medication use during pregnancy and the consequent cost implications. DESIGN: Retrospective analysis of case notes. SETTING: Labour wards, tertiary referral hospital, Royal Infirmary Edinburgh, UK. Population Six hundred and fifty-one women with a singleton pregnancy over four separate time periods in 2007 and 2008. METHODS: Descriptive statistics, univariate and multivariate logistic regression analysis and cost analysis using standard techniques and inflation indices. MAIN OUTCOME MEASURES: Minor complications, use of medications during pregnancy and consequent incremental costs from the perspective of the National Health Service (NHS). RESULTS: 42.4% of women were overweight or obese (BMI &gt; or = 25 kg/m(2)). Higher BMI during the first trimester (BMI &gt; or = 30 kg/m(2) compared with BMI &lt; 25 kg/m(2)) was associated with an increased risk of minor complications including symphysis pubis dysfunction (OR 3.97; 95% CI 2.19-7.18), heartburn (OR 2.65; 95% CI 1.42-4.94) and chest infection (OR 8.71; 95% 2.20-34.44) and with drugs used to treat these complications including Gaviscon (OR 3.52; 95% CI 1.78-6.96). The mean incremental (additional) NHS costs per woman for treating minor complications increased with maternal BMI were 15.45 pounds/woman, 17.64 pounds/woman and 48.66 pounds/woman for BMI &lt; 25 kg/m(2), BMI &gt; or = 25 to &lt;30 kg/m(2) and BMI &gt; or = 30 kg/m(2) respectively. CONCLUSIONS: Increased maternal BMI is associated with increased risk of developing minor complications during pregnancy; use of medications associated with treating these conditions and has significant NHS costs.</style></abstract></record></records></xml>