<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Kemme, Michiel J B</style></author><author><style face="normal" font="default" size="100%">Burggraaf, Jacobus</style></author><author><style face="normal" font="default" size="100%">Schoemaker, Rik C</style></author><author><style face="normal" font="default" size="100%">Cohen, Adam F</style></author><author><style face="normal" font="default" size="100%">Kluft, Cornelis</style></author><author><style face="normal" font="default" size="100%">Chia, Stanley</style></author><author><style face="normal" font="default" size="100%">Webb, David J</style></author><author><style face="normal" font="default" size="100%">Newby, David E</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Local tissue factor pathway inhibitor release in the human forearm.</style></title><secondary-title><style face="normal" font="default" size="100%">Thrombosis and haemostasis</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2003</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2003 Mar</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">89</style></volume><pages><style face="normal" font="default" size="100%">438-45</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">{Nineteen healthy men received unilateral brachial artery infusions of either unfractioned heparin (0.3-100 IU/min), saline or the endothelium-dependent vasodilators substance P (2-8 pmol/min) and bradykinin (100-1000 pmol/min), and the endothelium-independent vasodilator sodium nitroprusside (2-8 micro g/min). Heparin caused a dose-dependent increase in plasma TFPI concentrations in both arms (ANOVA, p &lt;0.0001). Estimated net forearm TFPI release was 7 +/- 16, 29 +/- 20 and 138 +/- 72 ng/100 mL tissue/min during 10, 30 and 100 IU/min of heparin respectively (ANOVA, p &lt;0.0001). Compared to the systemic circulation, the forearm sensitivity to heparin induced TFPI release was 3.6-fold lower (166 +/- 67 ng/IU vs. 596 +/- 252 ng/IU: t-test</style></abstract></record></records></xml>