Publications

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2010
McNeilly AD, Macfarlane DP, O'Flaherty E, Livingstone DE, Mitić T, McConnell KM, et al. Bile acids modulate glucocorticoid metabolism and the hypothalamic-pituitary-adrenal axis in obstructive jaundice. J Hepatol. 2010;52(5):705-11. Abstract
Malavasi EL, Kelly V, Nath N, Gambineri A, Dakin RS, Pagotto U, et al. Functional effects of polymorphisms in the human gene encoding 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1): a sequence variant at the translation start of 11 beta-HSD1 alters enzyme levels. Endocrinology. 2010;151(1):195-202. Abstract
Möller C, Melaun C, Castillo C, Díaz ME, Renzelman CM, Estrada O, et al. Functional hypervariability and gene diversity of cardioactive neuropeptides. J Biol Chem. 2010;285(52):40673-80. Abstract
2009
Carter RN, Paterson JM, Tworowska U, Stenvers DJ, Mullins JJ, Seckl JR, et al. Hypothalamic-pituitary-adrenal axis abnormalities in response to deletion of 11beta-HSD1 is strain-dependent. J Neuroendocrinol. 2009;21(11):879-87. Abstract
2008
Sai S, Esteves CL, Kelly V, Michailidou Z, Anderson K, Coll AP, et al. Glucocorticoid regulation of the promoter of 11beta-hydroxysteroid dehydrogenase type 1 is indirect and requires CCAAT/enhancer-binding protein-beta. Mol Endocrinol. 2008;22(9):2049-60. Abstract
Clarke IJ, Sari IP, Qi Y, Smith JT, Parkington HC, Ubuka T, et al. Potent action of RFamide-related peptide-3 on pituitary gonadotropes indicative of a hypophysiotropic role in the negative regulation of gonadotropin secretion. Endocrinology. 2008;149(11):5811-21. Abstract
Pask AJ, McInnes KJ, Webb DR, Short RV. Topical oestrogen keratinises the human foreskin and may help prevent HIV infection. PLoS ONE. 2008;3(6):e2308. Abstract
2006
Morgan K, Sellar R, Pawson AJ, Lu Z-, Millar RP. Bovine and ovine gonadotropin-releasing hormone (GnRH)-II ligand precursors and type II GnRH receptor genes are functionally inactivated. Endocrinology. 2006;147(11):5041-51. Abstract
2005
Bujalska IJ, Draper N, Michailidou Z, Tomlinson JW, White PC, Chapman KE, et al. Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydroxysteroid dehydrogenase type 1. J Mol Endocrinol. 2005;34(3):675-84. Abstract
Pawson AJ, Maudsley S, Morgan K, Davidson L, Naor Z, Millar RP. Inhibition of human type i gonadotropin-releasing hormone receptor (GnRHR) function by expression of a human type II GnRHR gene fragment. Endocrinology. 2005;146(6):2639-49. Abstract
2004
Gault PM, Morgan K, Pawson AJ, Millar RP, Lincoln GA. Sheep exhibit novel variations in the organization of the mammalian type II gonadotropin-releasing hormone receptor gene. Endocrinology. 2004;145(5):2362-74. Abstract
Davidson L, Pawson AJ, López de Maturana R, Freestone SH, Barran P, Millar RP, et al. Gonadotropin-releasing hormone-induced activation of diacylglycerol kinase-zeta and its association with active c-src. J Biol Chem. 2004;279(12):11906-16. Abstract
Zhu Y, James RM, Peter A, Lomas C, Cheung F, Harrison DJ, et al. Functional Smoothened is required for expression of GLI3 in colorectal carcinoma cells. Cancer Lett. 2004;207(2):205-14. Abstract
2003
Pawson AJ, Morgan K, Maudsley SR, Millar RP. Type II gonadotrophin-releasing hormone (GnRH-II) in reproductive biology. Reproduction. 2003;126(3):271-8. Abstract
2002
Tucker CS, Hirono I, Aoki T. Molecular cloning and expression of CCAAT/enhancer binding proteins in Japanese flounder Paralichthys olivaceus. Dev Comp Immunol. 2002;26(3):271-82. Abstract
2000
Williams LJ, Lyons V, MacLeod I, Rajan V, Darlington GJ, Poli V, et al. C/EBP regulates hepatic transcription of 11beta -hydroxysteroid dehydrogenase type 1. A novel mechanism for cross-talk between the C/EBP and glucocorticoid signaling pathways. J Biol Chem. 2000;275(39):30232-9. Abstract
1998
Wilson JF, Erlandsson R. Sexing of human and other primate DNA. Biol Chem. 1998;379(10):1287-8. Abstract
Morrow JA, Collie IT, Dunbar DR, Walker GB, Shahid M, Hill DR. Molecular cloning and functional expression of the human glycine transporter GlyT2 and chromosomal localisation of the gene in the human genome. FEBS Lett. 1998;439(3):334-40. Abstract
McClive P, Pall G, Newton K, Lee M, Mullins J, Forrester L. Gene trap integrations expressed in the developing heart: insertion site affects splicing of the PT1-ATG vector. Dev Dyn. 1998;212(2):267-76. Abstract
1996
Voice MW, Seckl JR, Chapman KE. The sequence of 5' flanking DNA from the mouse 11 beta-hydroxysteroid dehydrogenase type 1 gene and analysis of putative transcription factor binding sites. Gene. 1996;181(1-2):233-5. Abstract
1995
Dunbar DR, Moonie PA, Jacobs HT, Holt IJ. Different cellular backgrounds confer a marked advantage to either mutant or wild-type mitochondrial genomes. Proc Natl Acad Sci USA. 1995;92(14):6562-6. Abstract
Leckie C, Chapman KE, Edwards CR, Seckl JR. LLC-PK1 cells model 11 beta-hydroxysteroid dehydrogenase type 2 regulation of glucocorticoid access to renal mineralocorticoid receptors. Endocrinology. 1995;136(12):5561-9. Abstract
1993
Dunbar DR, Moonie PA, Swingler RJ, Davidson D, Roberts R, Holt IJ. Maternally transmitted partial direct tandem duplication of mitochondrial DNA associated with diabetes mellitus. Hum Mol Genet. 1993;2(10):1619-24. Abstract
Heck MM, Pereira A, Pesavento P, Yannoni Y, Spradling AC, Goldstein LS. The kinesin-like protein KLP61F is essential for mitosis in Drosophila. J Cell Biol. 1993;123(3):665-79. Abstract
1990
Ikuta K, Kina T, MacNeil I, Uchida N, Peault B, Chien YH, et al. A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells. Cell. 1990;62(5):863-74. Abstract