| Title | Impairment of the autoregulation of renal hemodynamics and of the pressure-natriuresis relationship precedes the development of hypertension in Cyp1a1-Ren-2 transgenic rats. |
| Publication Type | Journal Article |
| Year of Publication | 2009 |
| Authors | Erbanová M, Thumová M, Husková Z, Vanecková I, Vanourková Z, Mullins JJ, Kramer HJ, Bürgelová M, Rakusan D, Cervenka L |
| Journal | Journal of hypertension |
| Volume | 27 |
| Issue | 3 |
| Pagination | 575-86 |
| Date Published | 2009 Mar |
| ISSN | 1473-5598 |
| Keywords | Aldosterone, Angiotensin II, Angiotensin II Type 1 Receptor Blockers, Animals, Blood Pressure, Cytochrome P-450 CYP1A1, Glomerular Filtration Rate, Hemodynamics, Homeostasis, Hypertension, Indoles, Kidney, Losartan, Male, Natriuresis, Rats, Rats, Transgenic, Receptor, Angiotensin, Type 1, Renal Circulation, Renin, Renin-Angiotensin System, Sodium, Time Factors |
| Abstract | The present study was performed to characterize the autoregulatory efficiency of renal blood flow and glomerular filtration rate and the pressure-natriuresis relationship in transgenic rats with inducible angiotensin II (ANG II)-dependent hypertension (Cyp1a1-Ren-2 rats). |
| Alternate Journal | J. Hypertens. |
