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Jonathan Manning

Profile

on
Title: 
Dr
Jonathan
Manning
Admin unit: 
Molecular Physiology
Job title: 
Bioinformatician
Contact email: 
Jonathan.Manning@ed.ac.uk
Telephone: 
0131 242 6700
Room: 
W3.01
Location: 
QMRI
Address: 
47 Little France Crescent

Research

Background: 

I completed my first degreee in Biochemistry at the University of Leeds, during which I spent a 'sandwich' year in the laboratory of Dr Matthew Farrer at the Mayo Clinic, Florida, working on the genetics of parkinsonism. My final year undergraduate project was spent examining the role of water molecules at protein-protein interfaces, under the supervision of Professor Simon Phillips. Subsequent to this I undertook a Masters programme in Bioinformatics at Leeds under Drs David Westhead and Richard Jackson. The supervisor for my PhD was Professor Geoff Barton at the University of Dundee. My research was focused on the prediction of functional sites in protein sequences. During my time at Dundee I developed a prediction algorithm for such sites, and gained valuable experience in the field of high-performance computing. I completed this work in 2007, starting work at the QMRI in Edinburgh in 2008, under the supervision of Dr Donald Dunbar and Professor John Mullins. I am currently funded by the British Heart Foundation's 'Centre of Research Excellence Award'.

Responsibilities: 

As for the other members of the Bioinformatics team, my role is predominantly to facilitate the work of researchers within the three centres of the QMRI, helping with data interpretation with a keen eye on publication. Within the group I have developed interests in Web 2.0 technologies, deploying and maintaining a group wiki, as well as developing a solution for biological data aggregation recently published as BioKb,and deployed for the renin-angiotensin system at raaswiki.org. I'm also responsible for the construction and maintenance of this website.

In addition to my primary role, I am a keen member of Edinburgh University's science media association, EUSci, regularly partipating in the EUSci podcast, and editing and writing for EUSci magazine.

Research images: 
Query/template alignment for homology modelling for a paper written on HSD2 - PubMed ID 20571110
Structure from a paper written on HSD2 - PubMed ID 20571110
Structure from PABP work done for Nicola Gray and Ross Anderson
Word cloud for RAASWiki- go to www.raaswiki.org